Matrusri Oriental College is a prestigious institution located in Jillellamudi, Andhra Pradesh, India. It is a part of the Sree Viswajananee Parishat Trust and was established in 1971. The college is affiliated to Acharya Nagarjuna University and Sri Venkateswara Vedic University for Sanskrit courses, as per the government policy change in 2013.

The college offers an integrated five-year Degree B.A. (OL) Course in Sanskrit and Telugu languages. The minimum qualification for admission is a pass in S.S.C. or its equivalent examination. The college is committed to the overall development of the students and emphasizes not only academic excellence but also universal love and brotherhood, which are the cardinal messages of Matrusri Anasuya Devi, widely known and worshipped as Jillellamudi AMMA.

The college has earned laurels, awards, gold medals, and other achievements at the University, State, and National levels in academics, elocution, and other contests in both Sanskrit and Telugu languages over several years.